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MediPoint: Knee Replacement - South American Analysis and Market Forecasts

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LONDON, Feb. 19, 2014 /PRNewswire/ -- Reportbuyer.com just published a new market research report:

MediPoint: Knee Replacement - South American Analysis and Market Forecasts

MediPoint: Knee Replacement - South American Analysis and Market Forecasts

Summary

The current knee replacement market is a crowded space, with an increasing number of companies offering a myriad of partial, primary/total, and revision prostheses to meet orthopedic surgeons' demands in the management of knee diseases, primarily osteoarthritis. Worldwide, the primary/total knee segment represents about 80–90% of the entire knee market, with the remainder being partial knee and revision knee. Overall, clinical data show that short- to medium-term survivorship is excellent after almost all common types of knee replacement, regardless of fixation, constraint, and bearing type. Future competition among vendors will be more likely to center on the instrumentation and the ancillary equipment, such as patient-specific instruments, navigation systems, and robotic systems.

Brazil's economy is booming on the back of a growing middle class and rising investment in the physical infrastructure. The medical devices market in Brazil is the largest in South America. In the past few years, a general easing of the import bureaucracy and the requirement to improve the quality and quantity of healthcare services available in Brazil have led to increased adoption of advanced medical technologies, such as total shoulder replacement implants.

Scope

- An overview of hypertension, which includes epidemiology, etiology, symptoms, diagnosis, pathology and treatment guidelines.
- Annualized South America Knee replacement market revenue and future forecasts from 2009 to 2011, forecast for 7 years to 2018.
- Investigation of current and future market competition for Knee replacement
- Insightful review of the key industry drivers, restraints and challenges as well as predicted impact of key events.
- Competitor assessment including device approval analysis and device sales forecasts.
- Marketed and pipeline product profiles covering efficiency, safety, clinical study details, device approvals, product positioning and device sales forecast.
- Analysis of unmet needs within the market and opportunities for future players.
- Technology trends evaluation to assess strength of pipeline.
- An overview of all devices in development including clinical study details, design and material selection considerations, efficacy reports, and device approval timelines.
- Company profiles including business description, financial overview and SWOT analysis.
- Coverage of key market players.
- Strategic assessment of the Knee replacement sector through market impact analysis, future market scenario and company analysis.
- Direct quotes from Key Opinion Leaders (KOL) as well as cardiologists

Reasons to buy

- Understand the trends shaping and driving South America Knee replacement market.
- Realize device preferences of physicians who have performed the tests already.
- Access market sizing, forecasts and quantified growth opportunities in South America Knee replacement market through 2018.
- Quantify candidate patient populations to better design product pricing & launch plans.
- Drive revenues, formulate effective sales and marketing strategies and gain in-depth understanding of the competitive landscape.
- Perform benchmarking analysis of growth opportunities against currently marketed products.
- Assess competitiveness of products in market by understanding the strengths and weaknesses of current competition.
- Take a comprehensive look at the market's device pipeline and identify promising, paradigm-shifting products.
- Create an effective counter-strategy to gain a competitive advantage against those currently in the market.
- Organize your sales and marketing efforts by identifying the market categories and segments that present the best opportunities for growth.
- What's the next big thing in South America Knee replacement market landscape? Identify, understand and capitalize.
1 Table of Contents
1 Table of Contents 7
1.1 List of Tables 12
1.2 List of Figures 18
2 Introduction 20
2.1 Catalyst 21
2.2 Related Reports 21
3 Disease Overview 22
3.1 Anatomy and Physiology 22
3.2 Pathophysiology 24
3.2.1 Overview 24
3.2.2 Primary Osteoarthritis 24
3.2.3 Rheumatoid Arthritis 25
3.2.4 Post-Traumatic Arthritis 26
3.2.5 Avascular Necrosis 26
3.3 Clinical Presentation 27
3.3.1 Diagnosis 27
3.4 Clinical Outcomes 28
3.4.1 Overview 28
3.4.2 Conservative Treatments 28
3.4.3 Joint-Preserving Treatments 30
3.4.4 Joint Replacement 32
3.5 Economic Impact 43
3.5.1 South America 44
4 Industry Overview 45
4.1 Procedural Trends 45
4.2 Market Access 47
4.2.1 Regulation 47
4.2.2 Adoption 48
4.2.3 Reimbursement 51
4.3 Regulatory Issues/Recalls 53
4.3.1 DePuy Orthopaedic's Diaphyseal Sleeve Components of the Limb Preservation System (LPS) 53
4.3.2 Stryker's ShapeMatch Cutting Guides 53
4.3.3 Smith & Nephew's Journey Uni Tibial Insert, Right Medial/Left Lateral 54
4.4 Mergers and Acquisitions/Key Partnerships 54
4.4.1 Stryker's Acquisition of MAKO Surgical 54
4.4.2 MicroPort Medical B.V.'s Acquisition of Wright Medical's OrthoRecon Business 54
4.4.3 Stryker's Extension of Co-Marketing Agreement with OrthoSensor 55
4.4.4 Blue Belt Technologies' Co-Marketing Agreement with DJO Surgical 55
4.4.5 Biomet and OrthoSensor Enter Into Co-Promotion Partnership 55
4.4.6 Italian Consortium 2IL Orthopaedics Acquires Corin Group 56
4.4.7 Smith & Nephew Acquires LifeModeler, Inc. (LMI) 56
4.5 Market Drivers, Opportunities, and Barriers 57
4.5.1 Market Drivers 57
4.5.2 Market Opportunities 62
4.5.3 Market Barriers 68
5 Competitive Assessment 73
5.1 Overview 73
5.2 Global Market Share 75
5.3 B. Braun 76
5.3.1 Primary Knee Replacement 76
5.3.2 Partial Knee Replacement 78
5.3.3 Revision Knee Replacement 79
5.3.4 SWOT Analysis 79
5.4 Biomet 80
5.4.1 Primary Knee Replacement 80
5.4.2 Partial Knee Replacement 83
5.4.3 Revision Knee Replacement 84
5.4.4 SWOT Analysis 85
5.5 DePuy Synthes 86
5.5.1 Primary Knee Replacement 86
5.5.2 Partial Knee Replacement 91
5.5.3 Revision Knee Replacement 92
5.5.4 SWOT Analysis 93
5.6 DJO Surgical 94
5.6.1 Primary Knee Replacement 94
5.6.2 Partial Knee Replacement 97
5.6.3 Revision Knee Replacement 97
5.6.4 SWOT Analysis 98
5.7 Exactech 99
5.7.1 Primary Knee Replacement 99
5.7.2 Partial Knee Replacement 100
5.7.3 Revision Knee Replacement 101
5.7.4 SWOT Analysis 101
5.8 Smith & Nephew 102
5.8.1 Primary Knee Replacement 102
5.8.2 Partial Knee Replacement 105
5.8.3 Revision Knee Replacement 105
5.8.4 SWOT Analysis 106
5.9 Stryker 107
5.9.1 Primary Knee Replacement 107
5.9.2 Partial Knee Replacement 110
5.9.3 Revision Knee Replacement 111
5.9.4 SWOT Analysis 112
5.10 Wright Medical (MicroPort) 113
5.10.1 Primary Knee Replacement 113
5.10.2 Revision Knee Replacement 115
5.10.3 SWOT Analysis 116
5.11 Zimmer 117
5.11.1 Primary Knee Replacement 117
5.11.2 Partial Knee Replacement 123
5.11.3 Revision Knee Replacement 123
5.11.4 SWOT Analysis 125
6 Unmet Needs 126
6.1 Availability of Long-Term Clinical Data 126
6.2 Complete Knee Platform 128
6.3 Need for Cost-Containment 130
6.4 Training for Computer Navigation Technologies 131
6.5 Continued Innovations in Instrumentation 133
6.6 Advanced Materials 134
6.7 Implants for Metal-Sensitive Patients 135
6.8 National Joint Registry 137
7 Pipeline Products 138
7.1 Overview 138
7.2 Biomet's Vanguard XP Total Knee System 138
7.3 Corentec's Lospa Total Knee System 139
7.4 NovoSource's NovoKnee 139
7.5 Pipeline Orthopedics' NEO PS Knee System 139
7.6 Bonovo Orthopedics' JMM Total Knee System 139
7.7 Corin Group's Unity Knee Systems 140
7.8 Kinamed's GEM Total Knee System 140
7.9 Emerge Medical 140
8 Current and Future Players 141
8.1 Trends in Corporate Strategy 141
8.2 Established Players 142
8.2.1 B. Braun 142
8.2.2 Biomet 144
8.2.3 Corin Group 147
8.2.4 DePuy Synthes 150
8.2.5 DJO Global 153
8.2.6 Exactech 156
8.2.7 Lima Corporate 159
8.2.8 Medacta 161
8.2.9 Smith & Nephew 163
8.2.10 Stryker 166
8.2.11 Waldemar LINK 171
8.2.12 Wright Medical Group (MicroPort) 173
8.2.13 Zimmer Holdings 176
8.2.14 Other Established Players 181
8.3 Emerging Players 182
8.3.1 Blue Belt Technologies 182
8.3.2 ConforMIS 184
8.3.3 MAKO Surgical 187
8.3.4 OmniLife science 189
8.3.5 Other Emerging Players 192
9 Market Outlooks 193
9.1 Brazil 193
10 Appendix 196
10.1 Abbreviations 196
10.2 Bibliography 198
10.3 Report Methodology 218
10.3.1 Overview 218
10.3.2 Coverage 218
10.3.3 Secondary Research 219
10.3.4 Forecasting Methodology 220
10.3.5 Primary Research - Key Opinion Leader Interviews 221
10.3.6 Expert Panel Validation 221
10.4 Physicians and Specialists Included in This Study 222
10.5 Physician Survey 224
10.6 About the Authors 225
10.6.1 Analysts 225
10.6.2 Bonnie Bain, Ph.D., Global Head of Healthcare 226
10.7 About MediPoint 227
10.8 About GlobalData 227
10.9 Disclaimer 227

1.1 List of Tables

Table 1: Risk Factors for Primary OA of the Knee 25
Table 2: Common Clinical Symptoms of Knee Arthritis 27
Table 3: Common Reasons for Failed Knee Implants 39
Table 4: Advantages of CAS 41
Table 5: Direct, Indirect, and Intangible Costs of Arthritis 43
Table 6: Common Reasons for Revision After Total and Partial Knee Replacement 69
Table 7: Product Profile - Columbus Total Knee System 77
Table 8: Product Profile - e.motion Total Knee System 78
Table 9: Product Profile - univation Unicondylar Knee System 78
Table 10: Product Profile - B. Braun's Revision Knee Replacement Systems 79
Table 11: SWOT Analysis - B. Braun's Knee Portfolio 79
Table 12: Product Profile - Vanguard Complete Knee System 81
Table 13: List of Select Clinical Studies - Vanguard Complete Knee System 81
Table 14: Product Profile - AGC Total Knee System 82
Table 15: List of Select Clinical Studies - AGC Total Knee System 83
Table 16: Product Profile - Biomet's Partial Knee Replacement Systems 84
Table 17: Product Profile - Biomet's Revision Knee Replacement Systems 84
Table 18: Select Clinical Study - Biomet's Revision Knee Replacement Systems 85
Table 19: SWOT Analysis - Biomet's Knee Portfolio 85
Table 20: Product Profile - LCS Complete Knee Systems 87
Table 21: List of Select Clinical Studies - LCS Complete Knee System 87
Table 22: Product Profile - Sigma Knee System 89
Table 23: List of Select Clinical Studies - Sigma Knee System 89
Table 24: Product Profile - Attune Knee System 90
Table 25: List of Select Clinical Studies - Attune Knee System 91
Table 26: Product Profile - Sigma HP Partial Knee System 91
Table 27: Product Profile - DePuy's Revision Knee Replacement Systems 92
Table 28: List of Select Clinical Studies - DePuy's Revision Knee Replacement Systems 93
Table 29: SWOT Analysis - DePuy's Knee Portfolio 93
Table 30: Product Profile - Movation Knee System 94
Table 31: Product Profile - 3D Knee System 95
Table 32: Product Profile - Foundation Knee System 96
Table 33: Product Profile - EPIK Knee System 97
Table 34: Product Profile - Foundation Revision Knee System 97
Table 35: SWOT Analysis - DJO's Knee Portfolio 98
Table 36: Product Profile - Optetrak Knee System 100
Table 37: Product Profile - Optetrak Unicondylar Knee System 100
Table 38: Product Profile - Optetrack Constrained Condylar (CC) Knee System 101
Table 39: SWOT Analysis - Exactech's Knee Portfolio 101
Table 40: Product Profile - LEGION Knee System 103
Table 41: List of Select Clinical Studies - GENESIS II Total Knee System 103
Table 42: Product Profile - JOURNEY Knee System 104
Table 43: List of Select Clinical Studies - JOURNEY Knee System 104
Table 44: Product Profile - Smith & Nephew's Partial Knee Replacement Systems 105
Table 45: Product Profile - Smith & Nephew's Revision Knee Systems 106
Table 46: SWOT Analysis - Smith & Nephew's Knee Portfolio 106
Table 47: Product Profile - Triathlon Total Knee System 108
Table 48: List of Select Clinical Studies - Triathlon Total Knee System 108
Table 49: Product Profile - Scorpio Knee System 109
Table 50: Product Profile - Stryker's Partial Knee Replacement Systems 110
Table 51: Product Profile - Stryker's Revision Knee Replacement Systems 111
Table 52: Select Clinical Study - Stryker's Revision Knee Replacement System 111
Table 53: SWOT Analysis - Stryker's Knee Portfolio 112
Table 54: Product Profile - Advance Knee System 114
Table 55: Product Profile - Evolution Medial-Pivot Knee System 115
Table 56: Product Profile - Wright Medical's Revision Knee Replacement Systems 115
Table 57: SWOT Analysis - Wright Medical's Knee Portfolio 116
Table 58: Product Profile - NexGen Knee System 118
Table 59: List of Select Clinical Studies - NexGen Knee System 119
Table 60: Product Profile - Gender Solutions Knee Systems 120
Table 61: List of Select Clinical Studies - Gender Solutions' Knee System 120
Table 62: Product Profile - Persona Knee System 122
Table 63: List of Select Clinical Studies - Persona Knee System 122
Table 64: Product Profile - Zimmer's Partial Knee Replacement Systems 123
Table 65: Product Profile - Zimmer's Revision Knee Replacement Systems 124
Table 66: SWOT Analysis - Zimmer's Knee Portfolio 125
Table 67: Pipeline Products in the Global Knee Replacement Market, 2013 138
Table 68: Company Profile - B. Braun 142
Table 69: Portfolio Assessment - B. Braun 143
Table 70: SWOT Analysis - B. Braun 144
Table 71: Company Profile - Biomet 145
Table 72: Portfolio Assessment - Biomet 146
Table 73: SWOT Analysis - Biomet 147
Table 74: Company Profile - Corin Group 148
Table 75: Portfolio Assessment - Corin Group 149
Table 76: SWOT Analysis - Corin Group 149
Table 77: Company Profile - DePuy Synthes 151
Table 78: Portfolio Assessment - DePuy Synthes 152
Table 79: SWOT Analysis - DePuy Synthes 153
Table 80: Company Profile - DJO Global 154
Table 81: Portfolio Assessment - DJO Global 155
Table 82: SWOT Analysis - DJO Global 155
Table 83: Company Profile - Exactech 156
Table 84: Portfolio Assessment - Exactech 157
Table 85: SWOT Analysis - Exactech 158
Table 86: Company Profile - Lima Corporate 159
Table 87: Portfolio Assessment - Lima Corporate 160
Table 88: SWOT Analysis - Lima Corporate 160
Table 89: Company Profile - Medacta 161
Table 90: Portfolio Assessment - Medacta 162
Table 91: SWOT Analysis - Medacta 162
Table 92: Company Profile - Smith & Nephew 164
Table 93: Portfolio Assessment - Smith & Nephew 165
Table 94: SWOT Analysis - Smith & Nephew 166
Table 95: Company Profile - Stryker 167
Table 96: Portfolio Assessment - Stryker 169
Table 97: SWOT Analysis - Stryker 170
Table 98: Company Profile - Waldemar LINK 171
Table 99: Portfolio Assessment - Waldemar LINK 172
Table 100: SWOT Analysis - Waldemar LINK 172
Table 101: Company Profile - Wright Medical Group 174
Table 102: Portfolio Assessment - Wright Medical Group 175
Table 103: SWOT Analysis - Wright Medical Group 176
Table 104: Company Profile - Zimmer Holdings 177
Table 105: Portfolio Assessment - Zimmer Holdings 179
Table 106: SWOT Analysis - Zimmer Holdings 180
Table 107: Other Established Players in the Global Knee Replacement Market, 2013 181
Table 108: Company Profile - Blue Belt Technologies 182
Table 109: Portfolio Assessment - Blue Belt Technologies 183
Table 110: SWOT Analysis - Blue Belt Technologies 184
Table 111: Company Profile - ConforMIS 185
Table 112: Portfolio Assessment - ConforMIS 186
Table 113: SWOT Analysis - ConforMIS 186
Table 114: Company Profile - MAKO Surgical 187
Table 115: Portfolio Assessment - MAKO Surgical 188
Table 116: SWOT Analysis - MAKO Surgical 189
Table 117: Company Profile - OMNIlife science 190
Table 118: Portfolio Assessment - OMNIlife science 191
Table 119: SWOT Analysis - OMNIlife science 191
Table 120: Other Emerging Players in the Global Knee Replacement Market, 2013 192
Table 121: Brazil Knee Replacement Market Sales Forecast ($m), 2010-2019 193
Table 122: Abbreviations 196
Table 123: Physicians Surveyed, By Country 224

1.2 List of Figures
Figure 1: Schematic Diagram of Knee Anatomy 22
Figure 2: Unicompartmental Knee Replacement 33
Figure 3: Patellofemoral Knee Replacement 35
Figure 4: Bicompartmental Knee Replacement 36
Figure 5: CR and PS Designs 37
Figure 6: Knee Replacement Procedure Volume, Brazil, 2010-2019 45
Figure 7: Partial Knee Replacement Procedure Volume, Brazil, 2010-2019 46
Figure 8: Primary Knee Replacement Procedure Volume, Brazil, 2010-2019 46
Figure 9: Revision Knee Replacement Procedure Volume, Brazil, 2010-2019 47
Figure 10: Adoption Trend for Total Knee Implants in Brazil, Fixed-Bearing vs. Mobile-Bearing, 2011-2015 49
Figure 11: Adoption Trend for Total Knee Implants in Brazil, Cruciate-Retaining vs. Cruciate- Sacrificing, 2011-2015 49
Figure 12: Adoption Trend for Revision Knee Implants in Brazil, 2011-2015 50
Figure 13: Adoption Trend for Computer-Assisted Technologies in Brazil, 2012 51
Figure 14: Global Knee Replacement Market, Competitive Landscape by Sales Revenue, 2012 75
Figure 15: Columbus Total Knee System 76
Figure 16: e.motion Total Knee System 77
Figure 17: Vanguard Complete Knee System 80
Figure 18: AGC Total Knee System 82
Figure 19: LCS Complete Knee System 86
Figure 20: Sigma Knee System 88
Figure 21: Attune Knee System 90
Figure 22: Movation Knee System 94
Figure 23: 3D Knee System 95
Figure 24: Foundation Knee System 96
Figure 25: Optetrak Logic Knee System 99
Figure 26: GENESIS II Total Knee System 102
Figure 27: Journey Knee System 104
Figure 28: Triathlon Total Knee System 107
Figure 29: Scorpio Knee System 109
Figure 30: Advance Knee System 113
Figure 31: Evolution Medial-Pivot Knee System 114
Figure 32: NexGen Knee System 117
Figure 33: Gender Solutions' NexGen High-Flex Knee 120
Figure 34: Persona Knee System 121
Figure 35: Level of Impact of the Availability of Long-Term Clinical Data Upon Decision-Making (n=103) 127
Figure 36: Level of Impact of a Complete Knee System Upon Decision-Making (n=103) 128
Figure 37: Brazil Knee Replacement Market Sales Forecast ($m), 2010-2019 194
Figure 38: Brazil Primary Knee Replacement Market Segmentation by Type, 2012 and 2019 195

Companies Mentioned

B. Braun
Biomet
DePuy Synthes
DJO Surgical
Exactech
Smith & Nephew
Stryker
Wright Medical (MicroPort)
Zimmer

Read the full report:
MediPoint: Knee Replacement - South American Analysis and Market Forecasts
http://www.reportbuyer.com/pharma_healthcare/treatments/orthopaedic/medipoint_knee_replacement_south_american_analysis_market_forecasts.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Orthopedic

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